Sliding Filament Theory

Sliding Filament Theory 1. The binding of Ca2+ to troponin causes the tropomyosin-troponin complex to be rearranged This exposes the myosin-binding sites on the G actin 2. The ATP-bound myosin heads (low energy state) then hydrolyse ATP to ADP and Pi (high energy state) and bind to the G actin binding sites, forming crossbridges 3. When ADP and Pi are released, the myosin heads return to their low energy state and pull the thin filament towards the centre of the sarcomere 4. The crossbridge… More information...

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